Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury

High levels of circulating TNF and its receptors, TNFR1 and TNFR2, predict the progression of diabetic kidney disease (DKD), but their contribution to organ damage in DKD remains largely unknown. Here, we investigated the function of local and systemic TNF in podocyte injury. We cultured human podoc...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Clin Invest
Main Authors: Pedigo, Christopher E., Ducasa, Gloria Michelle, Leclercq, Farah, Sloan, Alexis, Mitrofanova, Alla, Hashmi, Tahreem, Molina-David, Judith, Ge, Mengyuan, Lassenius, Mariann I., Forsblom, Carol, Lehto, Markku, Groop, Per-Henrik, Kretzler, Matthias, Eddy, Sean, Martini, Sebastian, Reich, Heather, Wahl, Patricia, Ghiggeri, GianMarco, Faul, Christian, Burke, George W., Kretz, Oliver, Huber, Tobias B., Mendez, Armando J., Merscher, Sandra, Fornoni, Alessia
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004940/
https://ncbi.nlm.nih.gov/pubmed/27482889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85939
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍