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Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin
The membrane-anchored serine proteases prostasin (PRSS8) and matriptase (ST14) initiate a cell surface proteolytic pathway essential for epithelial function. Mice expressing only catalytically inactive prostasin are viable, unlike prostasin null mice, indicating that at least some prostasin function...
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| Publié dans: | Development |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004911/ https://ncbi.nlm.nih.gov/pubmed/27385010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137968 |
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