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Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin

The membrane-anchored serine proteases prostasin (PRSS8) and matriptase (ST14) initiate a cell surface proteolytic pathway essential for epithelial function. Mice expressing only catalytically inactive prostasin are viable, unlike prostasin null mice, indicating that at least some prostasin function...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Szabo, Roman, Lantsman, Taliya, Peters, Diane E., Bugge, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004911/
https://ncbi.nlm.nih.gov/pubmed/27385010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137968
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