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Plumbagin Protects Mice from Lethal Sepsis by Modulating Immunometabolism Upstream of PKM2
Sepsis is characterized by dysregulated systemic inflammation with release of early (for example, interleukin (IL)-1β) and late (for example, HMGB1) proinflammatory mediators from macrophages. Plumbagin, a medicinal plant-derived naphthoquinone, has been reported to exhibit antiinflammatory activity...
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| Publicado no: | Mol Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Feinstein Institute for Medical Research
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004715/ https://ncbi.nlm.nih.gov/pubmed/26982513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00250 |
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