Recombinant N–Terminal Slit2 Inhibits TGF-β–Induced Fibroblast Activation and Renal Fibrosis

Fibrosis and inflammation are closely intertwined injury pathways present in nearly all forms of CKD for which few safe and effective therapies exist. Slit glycoproteins signaling through Roundabout (Robo) receptors have been described to have anti-inflammatory effects through regulation of leukocyt...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Yuen, Darren A., Huang, Yi-Wei, Liu, Guang-Ying, Patel, Sajedabanu, Fang, Fei, Zhou, Joyce, Thai, Kerri, Sidiqi, Ahmad, Szeto, Stephen G., Chan, Lauren, Lu, Mingliang, He, Xiaolin, John, Rohan, Gilbert, Richard E., Scholey, James W., Robinson, Lisa A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2016
Konular:
Brief Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004640/
https://ncbi.nlm.nih.gov/pubmed/26869008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040356
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