Recombinant N–Terminal Slit2 Inhibits TGF-β–Induced Fibroblast Activation and Renal Fibrosis

Fibrosis and inflammation are closely intertwined injury pathways present in nearly all forms of CKD for which few safe and effective therapies exist. Slit glycoproteins signaling through Roundabout (Robo) receptors have been described to have anti-inflammatory effects through regulation of leukocyt...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Yuen, Darren A., Huang, Yi-Wei, Liu, Guang-Ying, Patel, Sajedabanu, Fang, Fei, Zhou, Joyce, Thai, Kerri, Sidiqi, Ahmad, Szeto, Stephen G., Chan, Lauren, Lu, Mingliang, He, Xiaolin, John, Rohan, Gilbert, Richard E., Scholey, James W., Robinson, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004640/
https://ncbi.nlm.nih.gov/pubmed/26869008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040356
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