SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling

Macropinocytosis is essential for myeloid cells to survey their environment and for growth of RAS-transformed cancer cells. Several growth factors and inflammatory stimuli are known to induce macropinocytosis, but its endogenous inhibitors have remained elusive. Stimulation of Roundabout receptors b...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Bhosle, Vikrant K., Mukherjee, Tapas, Huang, Yi-Wei, Patel, Sajedabanu, Pang, Bo Wen (Frank), Liu, Guang-Ying, Glogauer, Michael, Wu, Jane Y., Philpott, Dana J., Grinstein, Sergio, Robinson, Lisa A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431850/
https://ncbi.nlm.nih.gov/pubmed/32807784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17651-1
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