RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

During morphogenesis, contraction of the actomyosin cytoskeleton within individual cells drives cell shape changes that fold tissues. Coordination of cytoskeletal contractility is mediated by regulating RhoA GTPase activity. Guanine nucleotide exchange factors (GEFs) activate and GTPase-activating p...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Mason, Frank M., Xie, Shicong, Vasquez, Claudia G., Tworoger, Michael, Martin, Adam C.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004446/
https://ncbi.nlm.nih.gov/pubmed/27551058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603077
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