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A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction

Recent studies have demonstrated a novel molecular mechanism for the regulation of airway smooth muscle (ASM) contraction by RhoA GTPase. In ASM tissues both MLC phosphorylation and actin polymerization are required for active tension generation. RhoA inactivation dramatically suppresses agonist ind...

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Bibliografiske detaljer
Udgivet i:Can J Physiol Pharmacol
Main Authors: Zhang, Wenwu, Huang, Youliang, Wu, Yidi, Gunst, Susan J
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399233/
https://ncbi.nlm.nih.gov/pubmed/25531582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2014-0388
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