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A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction

Recent studies have demonstrated a novel molecular mechanism for the regulation of airway smooth muscle (ASM) contraction by RhoA GTPase. In ASM tissues both MLC phosphorylation and actin polymerization are required for active tension generation. RhoA inactivation dramatically suppresses agonist ind...

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Detalhes bibliográficos
Publicado no:Can J Physiol Pharmacol
Main Authors: Zhang, Wenwu, Huang, Youliang, Wu, Yidi, Gunst, Susan J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399233/
https://ncbi.nlm.nih.gov/pubmed/25531582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2014-0388
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