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RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

During morphogenesis, contraction of the actomyosin cytoskeleton within individual cells drives cell shape changes that fold tissues. Coordination of cytoskeletal contractility is mediated by regulating RhoA GTPase activity. Guanine nucleotide exchange factors (GEFs) activate and GTPase-activating p...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mason, Frank M., Xie, Shicong, Vasquez, Claudia G., Tworoger, Michael, Martin, Adam C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004446/
https://ncbi.nlm.nih.gov/pubmed/27551058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603077
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