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Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation

Sickle cell anemia is a manifestation of a single point mutation in hemoglobin, but inflammation and pain are the insignia of this disease which can start in infancy and continue throughout life. Earlier studies showed that mast cell activation contributes to neurogenic inflammation and pain in sick...

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Dettagli Bibliografici
Pubblicato in:Haematologica
Autori principali: Vincent, Lucile, Vang, Derek, Nguyen, Julia, Benson, Barbara, Lei, Jianxun, Gupta, Kalpna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004356/
https://ncbi.nlm.nih.gov/pubmed/26703965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.136523
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