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Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia

Pain is a hallmark feature of sickle cell anemia (SCA) but management of chronic as well as acute pain remains a major challenge. Mouse models of SCA are essential to examine the mechanisms of pain and develop novel therapeutics. To facilitate this effort, we compared humanized homozygous BERK and T...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lei, Jianxun, Benson, Barbara, Tran, Huy, Ofori-Acquah, Solomon F., Gupta, Kalpna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975462/
https://ncbi.nlm.nih.gov/pubmed/27494522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160608
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