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Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in A549 cells

KRAS mutant lung cancers have long been considered as untreatable with drugs. Transforming growth factor-β-activated kinase 1 (TAK1) appears to play an anti-apoptotic role in response to multiple stresses and has been reported to be a responsive kinase that regulates cell survival in KRAS-dependent...

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Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Li, Peng, Zhao, Qing-Li, Jawaid, Paras, Rehman, Mati Ur, Sakurai, Hiroaki, Kondo, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003804/
https://ncbi.nlm.nih.gov/pubmed/27448221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0712-6
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