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Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease

Key challenges faced by all cells include how to spatiotemporally organize complex biochemistry and how to respond to environmental fluctuations. The budding yeast Saccharomyces cerevisiae harnesses alternative protein folding mediated by yeast prion domains (PrDs) for rapid evolution of new traits...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: March, Zachary M., King, Oliver D., Shorter, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003744/
https://ncbi.nlm.nih.gov/pubmed/26996412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.02.037
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