Personalized Fludarabine Dosing To Reduce Non-Relapse Mortality In Hematopoietic Stem Cell Transplant Recipients Receiving Reduced Intensity Conditioning

Patients undergoing hematopoietic cell transplantation (HCT) with reduced intensity conditioning (RIC) commonly receive fludarabine. Higher exposure of F-ara-A, the active component of fludarabine, has been associated with a greater risk of non-relapse mortality (NRM). We sought to develop a model f...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Sanghavi, Kinjal, Wiseman, Anthony, Kirstein, Mark N., Cao, Qing, Brundage, Richard, Jensen, Kyle, Rogosheske, John, Kurtzweil, Andy, Long-Boyle, Janel, Wagner, John, Warlick, Erica D., Brunstein, Claudio G, Weisdorf, Daniel J., Jacobson, Pamala A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003687/
https://ncbi.nlm.nih.gov/pubmed/27094990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2016.03.017
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