High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation

Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined. Our objective of this study was to evaluate the association betwe...

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Detalhes bibliográficos
Main Authors: Long-Boyle, Janel R, Green, Kathleen G.E., Brunstein, Claudio G., Cao, Qing, Rogosheske, John, Weisdorf, Daniel J., Miller, Jeffrey S., Wagner, John E, McGlave, Philip B., Jacobson, Pamala A
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904846/
https://ncbi.nlm.nih.gov/pubmed/20383215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2010.53
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