Urinary Glycosaminoglycans Predict Outcomes in Septic Shock and Acute Respiratory Distress Syndrome

Rationale: Degradation of the endothelial glycocalyx, a glycosaminoglycan (GAG)-rich layer lining the vascular lumen, is associated with the onset of kidney injury in animal models of critical illness. It is unclear if similar pathogenic degradation occurs in critically ill patients. Objectives: To...

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Publicado en:Am J Respir Crit Care Med
Main Authors: Schmidt, Eric P., Overdier, Katherine H., Sun, Xiaojun, Lin, Lei, Liu, Xinyue, Yang, Yimu, Ammons, Lee Anne, Hiller, Terra D., Suflita, Matt A., Yu, Yanlei, Chen, Yin, Zhang, Fuming, Cothren Burlew, Clay, Edelstein, Charles L., Douglas, Ivor S., Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2016
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003330/
https://ncbi.nlm.nih.gov/pubmed/26926297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201511-2281OC
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