Urinary Glycosaminoglycans Predict Outcomes in Septic Shock and Acute Respiratory Distress Syndrome

Rationale: Degradation of the endothelial glycocalyx, a glycosaminoglycan (GAG)-rich layer lining the vascular lumen, is associated with the onset of kidney injury in animal models of critical illness. It is unclear if similar pathogenic degradation occurs in critically ill patients. Objectives: To...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Schmidt, Eric P., Overdier, Katherine H., Sun, Xiaojun, Lin, Lei, Liu, Xinyue, Yang, Yimu, Ammons, Lee Anne, Hiller, Terra D., Suflita, Matt A., Yu, Yanlei, Chen, Yin, Zhang, Fuming, Cothren Burlew, Clay, Edelstein, Charles L., Douglas, Ivor S., Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003330/
https://ncbi.nlm.nih.gov/pubmed/26926297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201511-2281OC
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