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The Circulating Glycosaminoglycan Signature of Respiratory Failure in Critically Ill Adults

Systemic inflammatory illnesses (such as sepsis) are marked by degradation of the endothelial glycocalyx, a layer of glycosaminoglycans (including heparan sulfate, chondroitin sulfate, and hyaluronic acid) lining the vascular lumen. We hypothesized that different pathophysiologic insults would produ...

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Autori principali: Schmidt, Eric P., Li, Guoyun, Li, Lingyun, Fu, Li, Yang, Yimu, Overdier, Katherine H., Douglas, Ivor S., Linhardt, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961648/
https://ncbi.nlm.nih.gov/pubmed/24509853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539452
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