A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin

Rationale: A genetic locus within the FAM13A gene has been consistently associated with chronic obstructive pulmonary disease (COPD) in genome-wide association studies. However, the mechanisms by which FAM13A contributes to COPD susceptibility are unknown. Objectives: To determine the biologic funct...

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Publicat a:Am J Respir Crit Care Med
Autors principals: Jiang, Zhiqiang, Lao, Taotao, Qiu, Weiliang, Polverino, Francesca, Gupta, Kushagra, Guo, Feng, Mancini, John D., Naing, Zun Zar Chi, Cho, Michael H., Castaldi, Peter J., Sun, Yang, Yu, Jane, Laucho-Contreras, Maria E., Kobzik, Lester, Raby, Benjamin A., Choi, Augustine M. K., Perrella, Mark A., Owen, Caroline A., Silverman, Edwin K., Zhou, Xiaobo
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003213/
https://ncbi.nlm.nih.gov/pubmed/26862784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201505-0999OC
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