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Synthesis of a novel photoactivatable glucosylceramide cross-linker

The biosynthesis of glucosylceramide (GlcCer) is a key rate-limiting step in complex glycosphingolipid (GSL) biosynthesis. To further define interacting partners of GlcCer, we have made a cleavable, biotinylated, photoreactive GlcCer analog in which the reactive nitrene is closely apposed to the Glc...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Main Authors: Budani, Monique, Mylvaganam, Murugesapillai, Binnington, Beth, Lingwood, Clifford
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003150/
https://ncbi.nlm.nih.gov/pubmed/27412675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D069609
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