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Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling
Statins, which specifically inhibit HMG Co-A reductase, the rate-limiting step of cholesterol biosynthesis, are widely prescribed to reduce serum cholesterol and cardiac risk, but many other effects are seen. We now show an effect of these drugs to induce profound changes in the step-wise synthesis...
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| Publicado no: | Glycobiology |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691287/ https://ncbi.nlm.nih.gov/pubmed/26405105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwv084 |
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