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Early Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility?
BACKGROUND: Many cancer biomarker research studies seek to develop markers that can accurately detect or predict future onset of disease. To design and evaluate these studies one must specify the levels of accuracy sought. However, justified target levels are rarely available. METHODS: We describe a...
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| Publicado en: | Clin Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5003106/ https://ncbi.nlm.nih.gov/pubmed/27001493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2015.252163 |
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