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Early Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility?

BACKGROUND: Many cancer biomarker research studies seek to develop markers that can accurately detect or predict future onset of disease. To design and evaluate these studies one must specify the levels of accuracy sought. However, justified target levels are rarely available. METHODS: We describe a...

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Detaylı Bibliyografya
Yayımlandı:Clin Chem
Asıl Yazarlar: Pepe, Margaret S., Janes, Holly, Li, Christopher I., Bossuyt, Patrick M., Feng, Ziding, Hilden, Jørgen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003106/
https://ncbi.nlm.nih.gov/pubmed/27001493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2015.252163
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