Female mice lacking Xist RNA show partial dosage compensation and survive to term

X-chromosome inactivation (XCI) compensates for differences in X-chromosome number between male and female mammals. XCI is orchestrated by Xist RNA, whose expression in early development leads to transcriptional silencing of one X chromosome in the female. Knockout studies have established a require...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Yang, Lin, Kirby, James E., Sunwoo, Hongjae, Lee, Jeannie T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002979/
https://ncbi.nlm.nih.gov/pubmed/27542829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.281162.116
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