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Female mice lacking Xist RNA show partial dosage compensation and survive to term
X-chromosome inactivation (XCI) compensates for differences in X-chromosome number between male and female mammals. XCI is orchestrated by Xist RNA, whose expression in early development leads to transcriptional silencing of one X chromosome in the female. Knockout studies have established a require...
Shranjeno v:
| izdano v: | Genes Dev |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5002979/ https://ncbi.nlm.nih.gov/pubmed/27542829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.281162.116 |
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