Hyperinsulinemia augments endothelin‐1 protein expression and impairs vasodilation of human skeletal muscle arterioles

Hyperinsulinemia is a hallmark of insulin resistance‐associated metabolic disorders. Under physiological conditions, insulin maintains a balance between nitric oxide (NO) and, the potent vasoconstrictor, endothelin‐1 (ET‐1). We tested the hypothesis that acute hyperinsulinemia will preferentially au...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Mahmoud, Abeer M., Szczurek, Mary R., Blackburn, Brian K., Mey, Jacob T., Chen, Zhenlong, Robinson, Austin T., Bian, Jing‐Tan, Unterman, Terry G., Minshall, Richard D., Brown, Michael D., Kirwan, John P., Phillips, Shane A., Haus, Jacob M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002909/
https://ncbi.nlm.nih.gov/pubmed/27796268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12895
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg