Hyperinsulinemia augments endothelin‐1 protein expression and impairs vasodilation of human skeletal muscle arterioles

Hyperinsulinemia is a hallmark of insulin resistance‐associated metabolic disorders. Under physiological conditions, insulin maintains a balance between nitric oxide (NO) and, the potent vasoconstrictor, endothelin‐1 (ET‐1). We tested the hypothesis that acute hyperinsulinemia will preferentially au...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Physiol Rep
Egile Nagusiak: Mahmoud, Abeer M., Szczurek, Mary R., Blackburn, Brian K., Mey, Jacob T., Chen, Zhenlong, Robinson, Austin T., Bian, Jing‐Tan, Unterman, Terry G., Minshall, Richard D., Brown, Michael D., Kirwan, John P., Phillips, Shane A., Haus, Jacob M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002909/
https://ncbi.nlm.nih.gov/pubmed/27796268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12895
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