Necroptosis promotes Staphylococcus aureus clearance by inhibiting excessive inflammatory signaling

Staphylococcus aureus trigger inflammation through inflammasome activation and recruitment of neutrophils, responses critical for pathogen clearance but associated with substantial tissue damage. We postulated that necroptosis, cell death mediated by the RIPK1/RIPK3/MLKL pathway, would function to l...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Kitur, Kipyegon, Wachtel, Sarah, Brown, Armand, Wickersham, Matthew, Paulino, Franklin, Peñaloza, Hernán F., Soong, Grace, Bueno, Susan, Parker, Dane, Prince, Alice
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001919/
https://ncbi.nlm.nih.gov/pubmed/27524612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.039
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