Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

Staphylococcus aureus USA300 strains cause a highly inflammatory necrotizing pneumonia. The virulence of this strain has been attributed to its expression of multiple toxins that have diverse targets including ADAM10, NLRP3 and CD11b. We demonstrate that induction of necroptosis through RIP1/RIP3/ML...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Kitur, Kipyegon, Parker, Dane, Nieto, Pamela, Ahn, Danielle S., Cohen, Taylor S., Chung, Samuel, Wachtel, Sarah, Bueno, Susan, Prince, Alice
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399879/
https://ncbi.nlm.nih.gov/pubmed/25880560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004820
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