Necroptosis promotes Staphylococcus aureus clearance by inhibiting excessive inflammatory signaling

Staphylococcus aureus trigger inflammation through inflammasome activation and recruitment of neutrophils, responses critical for pathogen clearance but associated with substantial tissue damage. We postulated that necroptosis, cell death mediated by the RIPK1/RIPK3/MLKL pathway, would function to l...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Kitur, Kipyegon, Wachtel, Sarah, Brown, Armand, Wickersham, Matthew, Paulino, Franklin, Peñaloza, Hernán F., Soong, Grace, Bueno, Susan, Parker, Dane, Prince, Alice
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001919/
https://ncbi.nlm.nih.gov/pubmed/27524612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.039
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