Necroptosis promotes Staphylococcus aureus clearance by inhibiting excessive inflammatory signaling

Staphylococcus aureus trigger inflammation through inflammasome activation and recruitment of neutrophils, responses critical for pathogen clearance but associated with substantial tissue damage. We postulated that necroptosis, cell death mediated by the RIPK1/RIPK3/MLKL pathway, would function to l...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Kitur, Kipyegon, Wachtel, Sarah, Brown, Armand, Wickersham, Matthew, Paulino, Franklin, Peñaloza, Hernán F., Soong, Grace, Bueno, Susan, Parker, Dane, Prince, Alice
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001919/
https://ncbi.nlm.nih.gov/pubmed/27524612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.039
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