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Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage
Staphylococcus aureus USA300 strains cause a highly inflammatory necrotizing pneumonia. The virulence of this strain has been attributed to its expression of multiple toxins that have diverse targets including ADAM10, NLRP3 and CD11b. We demonstrate that induction of necroptosis through RIP1/RIP3/ML...
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| 發表在: | PLoS Pathog |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399879/ https://ncbi.nlm.nih.gov/pubmed/25880560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004820 |
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