Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism

Retinol (ROL), the alcohol form of vitamin A, is known to control cell fate decision of various types of stem cells in the form of its active metabolite, retinoic acid (RA). However, little is known about whether ROL has regulatory effects on colonic stem cells. We examined in this study the effect...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Matsumoto, Taichi, Mochizuki, Wakana, Nibe, Yoichi, Akiyama, Shintaro, Matsumoto, Yuka, Nozaki, Kengo, Fukuda, Masayoshi, Hayashi, Ayumi, Mizutani, Tomohiro, Oshima, Shigeru, Watanabe, Mamoru, Nakamura, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001647/
https://ncbi.nlm.nih.gov/pubmed/27564706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162049
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