Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon

To develop stem cell therapy for small intestinal (SI) diseases, it is essential to determine whether SI stem cells in culture retain their tissue regeneration capabilities. By using a heterotopic transplantation approach, we show that cultured murine SI epithelial organoids are able to reconstitute...

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Detalhes bibliográficos
Main Authors: Fukuda, Masayoshi, Mizutani, Tomohiro, Mochizuki, Wakana, Matsumoto, Taichi, Nozaki, Kengo, Sakamaki, Yuriko, Ichinose, Shizuko, Okada, Yukinori, Tanaka, Toshihiro, Watanabe, Mamoru, Nakamura, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197962/
https://ncbi.nlm.nih.gov/pubmed/25128495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.245233.114
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