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Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin
Ts3 is an alpha scorpion toxin from the venom of the Brazilian scorpion Tityus serrulatus. Ts3 binds to the domain IV voltage sensor of voltage-gated sodium channels (Na(v)) and slows dow n their fast inactivation. The covalent structure of Ts3 toxin is uncertain, and the structure of the folded pro...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001624/ https://ncbi.nlm.nih.gov/pubmed/27244051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603420 |
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