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Total Chemical Synthesis of Biologically Active Vascular Endothelial Growth Factor
[Image: see text] A 204 residue covalent-dimer vascular endothelial growth factor, with full mitogenic activity, was made by one-pot native chemical ligation from three unprotected peptide segments. The covalent structure of synthetic VEGF was confirmed by precise mass measurement, and the three dim...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478761/ https://ncbi.nlm.nih.gov/pubmed/21744452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201103237 |
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