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CHAI and LATAIE: new genetic diseases of CTLA-4 checkpoint insufficiency
CTLA-4 is a critical inhibitory “checkpoint” molecule of immune activation. Several recent reports have described patients with immune dysregulation and lymphoproliferative disease resulting from 2 different genetic diseases that directly or indirectly cause CTLA-4 deficiency. Numerous articles have...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Blood |
|---|---|
| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society of Hematology
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000841/ https://ncbi.nlm.nih.gov/pubmed/27418640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-04-712612 |
| Ετικέτες: |
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