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Development of immune checkpoint therapy for cancer
Since the early 20th century, immunologists have investigated mechanisms that protect vertebrates from damaging immune responses against self-antigens by mature lymphocytes, i.e., peripheral tolerance. These mechanisms have been increasingly delineated at the molecular level, ultimately culminating...
Gespeichert in:
| Veröffentlicht in: | J Exp Med |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547853/ https://ncbi.nlm.nih.gov/pubmed/31068379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182395 |
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