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Development of immune checkpoint therapy for cancer

Since the early 20th century, immunologists have investigated mechanisms that protect vertebrates from damaging immune responses against self-antigens by mature lymphocytes, i.e., peripheral tolerance. These mechanisms have been increasingly delineated at the molecular level, ultimately culminating...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Fritz, Jill M., Lenardo, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547853/
https://ncbi.nlm.nih.gov/pubmed/31068379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182395
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