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Next generation of immune checkpoint therapy in cancer: new developments and challenges

Immune checkpoints consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response. In cancer, immune checkpoint pathways are often activated to inhibit the nascent anti-tumor immune response. Immune checkpoint therapies act by blocking or stimulating thes...

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Bibliografische gegevens
Gepubliceerd in:J Hematol Oncol
Hoofdauteurs: Marin-Acevedo, Julian A., Dholaria, Bhagirathbhai, Soyano, Aixa E., Knutson, Keith L., Chumsri, Saranya, Lou, Yanyan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856308/
https://ncbi.nlm.nih.gov/pubmed/29544515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0582-8
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