Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities

The HIV-1 ribonuclease H (RNase H) function of the reverse transcriptase (RT) enzyme catalyzes the selective hydrolysis of the RNA strand of the RNA:DNA heteroduplex replication intermediate, and represents a suitable target for drug development. A particularly attractive approach is constituted by...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Pala, Nicolino, Esposito, Francesca, Rogolino, Dominga, Carcelli, Mauro, Sanna, Vanna, Palomba, Michele, Naesens, Lieve, Corona, Angela, Grandi, Nicole, Tramontano, Enzo, Sechi, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000766/
https://ncbi.nlm.nih.gov/pubmed/27556447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081371
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky