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Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure

The development of pharmacotherapeutics that reduce relapse to alcohol drinking in patients with alcohol dependence is of considerable research interest. Preclinical data support a role for nucleus accumbens (NAc) κ opioid receptors (KOR) in chronic intermittent ethanol (CIE) exposure-induced increa...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Rose, Jamie H., Karkhanis, Anushree N., Steiniger-Brach, Björn, Jones, Sara R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000614/
https://ncbi.nlm.nih.gov/pubmed/27472317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081216
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