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Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors

Acute ethanol exposure is known to stimulate the dopamine system; however, chronic exposure has been shown to downregulate the dopamine system. In rodents, chronic intermittent exposure (CIE) to ethanol also increases negative affect during withdrawal, such as, increases in anxiety- and depressive-l...

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Veröffentlicht in:Neuropharmacology
Hauptverfasser: Karkhanis, Anushree N., Huggins, Kimberly N., Rose, Jamie H., Jones, Sara R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028299/
https://ncbi.nlm.nih.gov/pubmed/27450094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.07.022
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