High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

BACKGROUND: The progression of colorectal cancer (CRC) involves recurrent amplifications/mutations in the epidermal growth factor receptor (EGFR) and downstream signal transducers of the Ras pathway, KRAS and BRAF. Whether genetic events predicted to result in increased and constitutive signaling in...

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Publicado en:BMC Cancer
Autores principales: Padhan, Narendra, Nordling, Torbjörn E. M., Sundström, Magnus, Åkerud, Peter, Birgisson, Helgi, Nygren, Peter, Nelander, Sven, Claesson-Welsh, Lena
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000422/
https://ncbi.nlm.nih.gov/pubmed/27562229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2725-z
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