High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

BACKGROUND: The progression of colorectal cancer (CRC) involves recurrent amplifications/mutations in the epidermal growth factor receptor (EGFR) and downstream signal transducers of the Ras pathway, KRAS and BRAF. Whether genetic events predicted to result in increased and constitutive signaling in...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Padhan, Narendra, Nordling, Torbjörn E. M., Sundström, Magnus, Åkerud, Peter, Birgisson, Helgi, Nygren, Peter, Nelander, Sven, Claesson-Welsh, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000422/
https://ncbi.nlm.nih.gov/pubmed/27562229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2725-z
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