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NHX-5, an Endosomal Na(+)/H(+) Exchanger, Is Associated with Metformin Action
Diabetes is one of the most impactful diseases worldwide. The most commonly prescribed anti-diabetic drug is metformin. In this study, we identified an endosomal Na(+)/H(+) exchanger (NHE) as a new potential target of metformin from an unbiased screen in Caenorhabditis elegans. The same NHE homolog...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000102/ https://ncbi.nlm.nih.gov/pubmed/27435670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.744037 |
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