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Controlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66

Phosphatase and tensin homolog (PTEN) is a phosphoinositide lipid phosphatase and one of the most frequently disrupted tumor suppressors in many forms of cancer, with even small reductions in the expression levels of PTEN promoting cancer development. Although the post-translational ubiquitination o...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Gupta, Amit, Leslie, Nicholas R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000091/
https://ncbi.nlm.nih.gov/pubmed/27405757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.727750
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