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Oxidative Inactivation of the Lipid Phosphatase Phosphatase and Tensin Homolog on Chromosome Ten (PTEN) as a Novel Mechanism of Acquired Long QT Syndrome

The most common cause of cardiac side effects of pharmaco-therapy is acquired long QT syndrome, which is characterized by abnormal cardiac repolarization and most often caused by direct blockade of the cardiac potassium channel human ether a-go-go-related gene (hERG). However, little is known about...

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Autores principales: Wan, Xiaoping, Dennis, Adrienne T., Obejero-Paz, Carlos, Overholt, Jeffrey L., Heredia-Moya, Jorge, Kirk, Kenneth L., Ficker, Eckhard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024780/
https://ncbi.nlm.nih.gov/pubmed/21097842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125526
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