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Controlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66

Phosphatase and tensin homolog (PTEN) is a phosphoinositide lipid phosphatase and one of the most frequently disrupted tumor suppressors in many forms of cancer, with even small reductions in the expression levels of PTEN promoting cancer development. Although the post-translational ubiquitination o...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Gupta, Amit, Leslie, Nicholas R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000091/
https://ncbi.nlm.nih.gov/pubmed/27405757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.727750
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