Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

Infection by the dengue virus (DENV) threatens global public health due to its high prevalence and the lack of effective treatments. Host factors may contribute to the pathogenesis of DENV; herein, we investigated the role of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), which is activated by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cheng, Yi-Lin, Lin, Yee-Shin, Chen, Chia-Ling, Tsai, Tsung-Ting, Tsai, Cheng-Chieh, Wu, Yan-Wei, Ou, Yi-Dan, Chu, Yu-Yi, Wang, Ju-Ming, Yu, Chia-Yi, Lin, Chiou-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999957/
https://ncbi.nlm.nih.gov/pubmed/27561946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32000
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