Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

Infection by the dengue virus (DENV) threatens global public health due to its high prevalence and the lack of effective treatments. Host factors may contribute to the pathogenesis of DENV; herein, we investigated the role of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), which is activated by...

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Vydáno v:Sci Rep
Hlavní autoři: Cheng, Yi-Lin, Lin, Yee-Shin, Chen, Chia-Ling, Tsai, Tsung-Ting, Tsai, Cheng-Chieh, Wu, Yan-Wei, Ou, Yi-Dan, Chu, Yu-Yi, Wang, Ju-Ming, Yu, Chia-Yi, Lin, Chiou-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999957/
https://ncbi.nlm.nih.gov/pubmed/27561946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32000
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