Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

Infection by the dengue virus (DENV) threatens global public health due to its high prevalence and the lack of effective treatments. Host factors may contribute to the pathogenesis of DENV; herein, we investigated the role of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), which is activated by...

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Publicat a:Sci Rep
Autors principals: Cheng, Yi-Lin, Lin, Yee-Shin, Chen, Chia-Ling, Tsai, Tsung-Ting, Tsai, Cheng-Chieh, Wu, Yan-Wei, Ou, Yi-Dan, Chu, Yu-Yi, Wang, Ju-Ming, Yu, Chia-Yi, Lin, Chiou-Feng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999957/
https://ncbi.nlm.nih.gov/pubmed/27561946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32000
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