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Pubertal Expression of α4βδ GABA(A) Receptors Reduces Seizure-Like Discharges in CA1 Hippocampus
More than half of children with epilepsy outgrow their seizures, yet the underlying mechanism is unknown. GABAergic inhibition increases at puberty in female mice due to expression of extrasynaptic α4βδ GABA(A) receptors (GABARs). Therefore, we tested the role of these receptors in regulating seizur...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4999950/ https://ncbi.nlm.nih.gov/pubmed/27561815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31928 |
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